Fusion Pharmaceuticals Inc.

A clinical stage company focused on developing novel radiotherapeutics for the treatment of cancer. Fusion is a spin-out from the Centre for Probe Development and Commercialization (CPDC) at McMaster University, Hamilton.

Fusion Pharmaceuticals Inc.Fusion Pharmaceuticals Inc.


Turnstone Biologics Inc.

Novel bio-therapeutics for the treatment of cancer: Turnstone Biologics extends the boundaries of the emerging field of cancer immunotherapy. Turnstone’s Maraba virus technology is a first-in-class tumour targeted oncolytic vaccine. Building on the recent clinical validation of OVs, the Maraba virus technology combines potent tumour killing effects with the benefits of a cancer vaccine, increasing anti-tumour immunity.

Turnstone Biologics Inc.Turnstone Biologics Inc.


Propellon Therapeutics Inc.

The development and commercialization of novel cancer therapies targeting the WDR5 protein, essential for assembly of methyltransferase complexes and proper histone modification. The overexpression of WDR5 and resulting deregulation of epigenetic mechanisms are implicated in various cancers and correlated with poor patient survival.

Propellon Therapeutics Inc.Propellon Therapeutics Inc.


Novera Therapeutics Inc.

A biotherapeutics company focused on developing and commercializing therapies that improve patient outcomes in difficult-to-treat cancers. Their current focus is on the development of promising small molecule drug candidates for haematological cancers.

Novera Therapeutics Inc.Novera Therapeutics Inc.


Fluorinov Pharma Inc. (acquired by Trillium Therapeutics)

This novel, best-in-class orally bioavailable proteosome inhibitor is being developed for the treatment of multiple myeloma and other cancers.

Fluorinov Pharma Inc. (acquired by Trillium Therapeutics)Fluorinov Pharma Inc. (acquired by Trillium Therapeutics)


Privacy Analytics Inc.

This software platform, called Privacy Analytics Risk Assessment Tool (PARAT), unlocks the vast potential of data on diseases and patient care without compromising individual privacy.

Privacy Analytics Inc.Privacy Analytics Inc.


Triphase Accelerator Corporation

An Accelerator enterprise formed to expedite proof-of-concept (PoC) and development of pre-IND cancer therapies, advancing in-licensed, clinically enabled oncology assets with high-value potential in a shared risk model for the purpose of out-licensing or selling the technology to create value. Triphase has formed a strategic partnership with Celgene Corporation to enable the rapid development of PoC in important new cancer therapies of mutual interest. 

Triphase Accelerator CorporationTriphase Accelerator Corporation


DVS Sciences Inc. (acquired by Fluidigm Sciences)

A unique analytical instrument for high throughput and highly multiplexed analyses of biomarkers for research, clinical trials and personalized medicine.

DVS Sciences Inc. (acquired by Fluidigm Sciences)DVS Sciences Inc. (acquired by Fluidigm Sciences)


2018: ReFilx™ – A regenerative filler matrix for breast cancer patients

ReFilx™ is a novel polymeric soft tissue filler that provides breast cancer patients with a cosmetically superior, minimally-invasive and cost-effective solution for the permanent restoration of breast defects following lumpectomy.

PITCH PRESENTER: Soror Sharifpoor, Polumiros Inc.

2018: ReFilx™ – A regenerative filler matrix for breast cancer patients2018: ReFilx™ – A regenerative filler matrix for breast cancer patients


2017: Development of a Multi-mechanistic Vaccinia Virus-based Platform for the Treatment of Pancreatic Cancer

The novel platform delivers sustained and amplified viral-mediated cell killing specific to pancreatic cancer (PCa) via the production of PCa cell-targeted amiR-containing exosomes.

PITCH PRESENTER: Brian Keller, Carolina Ilkow, The Ottawa Hospital Research Institute

2017: Development of a Multi-mechanistic Vaccinia Virus-based Platform for the Treatment of Pancreatic Cancer2017: Development of a Multi-mechanistic Vaccinia Virus-based Platform for the Treatment of Pancreatic Cancer


Inhibition of Kv1.3: Inducing Apoptosis and Impeding Cancer Cell Proliferation

Further development of promising potent compounds in triple-negative breast cancer models.

Inhibition of Kv1.3: Inducing Apoptosis and Impeding Cancer Cell ProliferationInhibition of Kv1.3: Inducing Apoptosis and Impeding Cancer Cell Proliferation


Universal CAR-T Therapy

Development of a universally compatible (allogeneic) source for the next generation of CAR-T therapies based on hematopoietic stem cells harvested from healthy donors.

Universal CAR-T TherapyUniversal CAR-T Therapy


ADC Linker Platform

Further development of novel cyclic and heterocyclic hydrazone-based linkers for antibody-drug-conjugates (ADC). These compounds allow “tuning” of the drug-release properties of the ADC to optimize various properties, such as plasma stability and lysosome drug release, according to the desired application(s).

ADC Linker PlatformADC Linker Platform


Test to Predict Breast Cancer Patient Response to Anthracyclines

Further validation of novel diagnostic gene test to predict which patients benefit from anthracycline chemotherapy.

Test to Predict Breast Cancer Patient Response to AnthracyclinesTest to Predict Breast Cancer Patient Response to Anthracyclines


Automatic Analysis of Screening Mammograms for Breast Cancer

Clinical validation of a novel breast cancer screening algorithm that can identify select screening mammograms as ‘benign and requiring no further review’, thereby reducing the need for a radiologist consult.

Automatic Analysis of Screening Mammograms for Breast CancerAutomatic Analysis of Screening Mammograms for Breast Cancer


DT1 Class of Agents for the Treatment of AML and Other Orphan Cancers

Development of DT-1 class of small molecules which possess selective cancer cell-killing activity and reduced toxicity due to a unique “cloaking” mechanism.

DT1 Class of Agents for the Treatment of AML and Other Orphan CancersDT1 Class of Agents for the Treatment of AML and Other Orphan Cancers


Development of a Cloud Platform for Genomics Data Management, Analysis and Sharing

The platform intends to make it easier for stakeholders to form public and private data sharing networks, and systematize genotype-phenotype associations, patient matching, and recruitment through deterministic search and machine learning algorithms.

Development of a Cloud Platform for Genomics Data Management, Analysis and SharingDevelopment of a Cloud Platform for Genomics Data Management, Analysis and Sharing


Multi-Spectral X-ray Panel for Chest Imaging

Development of multi-spectral X-ray imagers that improve the quality and accuracy of chest X-rays, while helping to reduce the demand for CT cancer diagnostics.

Multi-Spectral X-ray Panel for Chest ImagingMulti-Spectral X-ray Panel for Chest Imaging


Positron Emission Mammography (PEM) Imaging System to Detect Pre-Invasive Breast Cancers

Innovative solid-state PEM system that produces a higher resolution of the breast, while reducing radiotracer dose, compared to competitive PEM system.  

Positron Emission Mammography (PEM) Imaging System to Detect Pre-Invasive Breast CancersPositron Emission Mammography (PEM) Imaging System to Detect Pre-Invasive Breast Cancers


Heliotrope Bioinformatics Software Platform

A bioinformatics software platform that enables informed and actionable clinical decision by facilitating the interpretation and translation of tumor genomic sequencing data using comprehensive databases.

Heliotrope Bioinformatics Software PlatformHeliotrope Bioinformatics Software Platform


2016: MY-osto-ME

An economical port, bag and belt system for urostomy patients that aims to reduce their rate of complications, facilitate application, and reduce social stigma; overall helping improve the quality of life of bladder cancer patients.

PITCH PRESENTER: Dr. Nicholas Power, London Health Sciences Centre

2016: MY-osto-ME2016: MY-osto-ME


Cell Permeable Kv1.3 Antagonists: Novel Targeting of Apoptosis in Cancer Treatment

Evaluation of novel potassium channel antagonists, initially developed for neurodegenerative disorders, as cancer therapeutics. 

Cell Permeable Kv1.3 Antagonists: Novel Targeting of Apoptosis in Cancer TreatmentCell Permeable Kv1.3 Antagonists: Novel Targeting of Apoptosis in Cancer Treatment


Ganglioside-based Immonotherapy

Evaluation of survival benefit and preclinical proof of concept of a novel ganglioside-based cancer vaccine.

Ganglioside-based ImmonotherapyGanglioside-based Immonotherapy


CYP26 Inhibitors for Treatment of Acute Myeloid Leukemia

Development of novel CYP26 inhibitors for the treatment of leukemia and myeloma with potential greater specificity and less toxicity than current inhibitors.

CYP26 Inhibitors for Treatment of Acute Myeloid LeukemiaCYP26 Inhibitors for Treatment of Acute Myeloid Leukemia


2015: ChemoTracker

A mobile health application that seeks to merge tracking of patients’ side effects and situations related to cancer treatments with patient-provider communication.

PITCH PRESENTER: Danielle Paes, FocusONCare

2015: ChemoTracker2015: ChemoTracker


2014: Ultra-Low Dose Microbubbles for Cancer

A new manufacturing process that creates microbubbles that are only responsive to the ultrasound frequency used in cancer treatment, enabling significantly lower volumes and costs while potentially improving safety.

PITCH PRESENTER: Dr. Naomi Matsuura, Sunnybrook Research Institute

2014: Ultra-Low Dose Microbubbles for Cancer2014: Ultra-Low Dose Microbubbles for Cancer


Ring Study to Evaluate the PRedicTive brEast Cancer Test (PRoTECT)

Evaluation of a Nanostring gene expression assay across three centres for its analytical reproducibility and accuracy in potentially guiding the selection of patient-specific therapies for early breast cancers.

Ring Study to Evaluate the PRedicTive brEast Cancer Test (PRoTECT)Ring Study to Evaluate the PRedicTive brEast Cancer Test (PRoTECT)


External Clinical Validation Study of a Quantitative Ultrasound Spectral Analysis Platform

Use of clinical low frequency ultrasound for monitoring tumour response in women receiving neoadjuvant chemotherapy for locally advanced breast cancer.

External Clinical Validation Study of a Quantitative Ultrasound Spectral Analysis PlatformExternal Clinical Validation Study of a Quantitative Ultrasound Spectral Analysis Platform


A CEA Vaccine that Generates a Humoral Response to Break Tolerance

Evaluation of immune responses engendered in CEA transgenic mice by a vaccine formulation composed of a recombinant CEA N domain antigen and advanced adjuvant.

A CEA Vaccine that Generates a Humoral Response to Break ToleranceA CEA Vaccine that Generates a Humoral Response to Break Tolerance


Cell-Mate Technology for Esophageal Cell Sampling

Support for the use of Cell-Mate Technology in a clinical trial for the Genome Canada project entitled "Early detection of patients at high risk of esophageal adenocarcinoma".

Cell-Mate Technology for Esophageal Cell SamplingCell-Mate Technology for Esophageal Cell Sampling


Cellax Nanoparticles for Enhanced Cancer Treatment

CellaxTM is a drug-polymer conjugate nanoparticle that when injected, selectively accumulates in tumours resulting in increased therapeutic benefits and reduced side effects.

Cellax Nanoparticles for Enhanced Cancer TreatmentCellax Nanoparticles for Enhanced Cancer Treatment


Harmonic Medical Inc.

A system using ultrasound to both detect and treat tumours in bone and liver for the relief of pain without surgery and without expensive imaging equipment.

Harmonic Medical Inc.Harmonic Medical Inc.